Mesothelin anticorps (Middle Region)

N° du produit ABIN2775327

Détail du produit anti-Mesothelin anticorps

Antigène: Mesothelin (MSLN)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Porc, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: Western Blotting (WB)

Séquence: QKLLGPHVEG LKAEERHRPV RDWILRQRQD DLDTLGLGLQ GGIPNGYLVL

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MSLN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MSLN

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 622 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: MSLN (MSLN Produits)

Synonymes: anticorps MPF, anticorps SMRP, anticorps MSLN, anticorps mesothelin, anticorps MSLN, anticorps Msln, anticorps LOC611363, anticorps LOC100524016

Sujet: An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin.An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants.
Alias Symbols: CAK1, MPF, SMR, SMRP
Protein Interaction Partner: RSG1, MRPL1, RNMTL1, MRPL16, ZBTB43, MRPL28, LAMTOR3, RALA, NDUFB9, NDUFB5, MPV17, ATP6V1A, MUC16,
Protein Size: 622

Poids moléculaire: 32 kDa

ID gène: 10232

NCBI Accession: NM_005823, NP_005814

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process