UGT1A9 anticorps (N-Term)
Aperçu rapide pour UGT1A9 anticorps (N-Term) (ABIN2775485)
Antigène
Voir toutes UGT1A9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- LLMGSYNDIF DLFFSNCRSL FKDKKLVEYL KESSFDAVFL DPFDNCGLIV
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Homologie
- Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 100%, Sheep: 83%
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Attributs du produit
- This is a rabbit polyclonal antibody against UGT1A9. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human UGT1A9
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 530 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))
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Autre désignation
- UGT1A9
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Sujet
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UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. UGT1A9 is active on phenols.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HLUGP4, LUGP4, UDPGT, UGT1AI, UGT1I, UGT-1I, UGT1-9, UGT1.9, UGT1-09, UDPGT 1-9
Protein Size: 530 -
Poids moléculaire
- 57 kDa
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ID gène
- 54600
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NCBI Accession
- NM_021027, NP_066307
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UniProt
- O60656
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Pathways
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
Antigène
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