ZYX anticorps (Middle Region)

N° du produit ABIN2775767

L’anticorps Lapin Polyclonal anti-ZYX a été validé pour WB et IHC. Il convient pour détecter ZYX dans des échantillons de Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour ZYX anticorps (Middle Region) (ABIN2775767)

Antigène: ZYX (Zyxin (ZYX))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZYX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ZYX anticorps

Épitope: Middle Region

Séquence: QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ZYX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ZYX

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 572 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZYX

Antigène: ZYX (Zyxin (ZYX))

Autre désignation: ZYX

Sujet: TRIM50 is an E3 ubiquitin-protein ligase.Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
Alias Symbols: ESP-2, HED-2
Protein Interaction Partner: RTN4IP1, YPEL3, IMP3, PHF21A, PDLIM5, LIN7A, SUMO1, NEDD8, FAM129B, CORO1B, CAND1, PUF60, PAPOLA, NUDC, SEC23B, SEC24C, HIST1H4A, UGP2, TARS, PXN, GART, GARS, APEH, FN1, HIPK3, VCAM1, UBC, UBL7, UFC1, UBXN7, ZC3H7B, TTLL12, FERMT2, TOMM34, AHCYL1, SSSCA1,
Protein Size: 572

Poids moléculaire: 61 kDa

ID gène: 7791

NCBI Accession: NM_003461, NP_003452

UniProt: Q15942