EIF2A anticorps (C-Term)

N° du produit ABIN2776588

Cet anticorps anti-EIF2A est un anticorps Lapin Polyclonal détectant EIF2A dans WB et IHC. Adapté pour Humain, Souris, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Chévre, Cobaye et Poisson zèbre (Danio rerio). Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour EIF2A anticorps (C-Term) (ABIN2776588)

Antigène: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Chévre, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-EIF2A anticorps

Épitope: C-Term

Séquence: DKSPDLAPTP APQSTPRNTV SQSISGDPEI DKKIKNLKKK LKAIEQLKEQ

Homologie: Cow: 86%, Dog: 100%, Goat: 83%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against EIF2A. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 585 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-EIF2A (ABIN2776588)

Feng, Chen, Chan, Chen: "Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo." dans: Parkinson's disease, Vol. 2020, pp. 8814236, (2020) (PubMed).

Xu, Liu, Caffaro, Hirschberg: "Inhibition of Golgi apparatus glycosylation causes endoplasmic reticulum stress and decreased protein synthesis." dans: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24600-8, (2010) (PubMed).

Su, Wang, Baltzis, Qu, Wong, Koromilas: "Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 1, pp. 63-8, (2006) (PubMed).

Détails sur EIF2A

Antigène: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Autre désignation: EIF2A

Sujet: EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes.EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002).[supplied by OMIM].
Alias Symbols: CDA02, MST089, MSTP004, MSTP089, EIF-2A
Protein Interaction Partner: UBC, CDC20, RPS23, RPS19, RPS16, RPS10, RPS7, RPS5, HDLBP, PRUNE2, EIF3K, SERBP1, RPS29, RPS24, EIF2AK2, MLH1, NXF1, ILF3, PA2G4, APP, PPP1CC, NEDD8, DCC, ATF4,
Protein Size: 585

Poids moléculaire: 64 kDa

ID gène: 83939

NCBI Accession: NM_032025, NP_114414

UniProt: Q9BY44

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly