FZD10 anticorps (N-Term)

N° du produit ABIN2776713

Il existe 1 publication pour ce produit. L’anticorps anti-FZD10 Polyclonal Lapin est utilisé pour la détection de FZD10 dans des échantillons de Humain, Souris, Porc, Boeuf (Vache), Chien, Cheval et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour FZD10 anticorps (N-Term) (ABIN2776713)

Antigène: FZD10 (Frizzled Family Receptor 10 (FZD10))

Reactivité: Humain, Souris, Porc, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FZD10 anticorps

Épitope: N-Term

Fonction: FZD10 Antibody - N-terminal region

Séquence: PIEIPMCKDI GYNMTRMPNL MGHENQREAA IQLHEFAPLV EYGCHGHLRF

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FZD10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FZD10

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41262-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FZD10 (ABIN2776713)

Gonzalez, Fernandez-Martos, Gonzalez-Fernandez, Arenas, Rodriguez: "Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats." dans: PLoS ONE, Vol. 7, Issue 12, pp. e50793, (2012) (PubMed).

Détails sur FZD10

Antigène: FZD10 (Frizzled Family Receptor 10 (FZD10))

Autre désignation: FZD10

Sujet:

Background Information: FZD10 is a member of the frizzled family. Members of this family are 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.

Gene Name: Frizzled family receptor 10

Alternative Symbols: Fz10, FzE7, CD350, FZ-10, hFz10

Protein Name: Frizzled-10

Poids moléculaire: 65 kDa

ID gène: 11211

NCBI Accession: NP_009128

UniProt: Q9ULW2

Pathways: Signalisation WNT