Aurora A anticorps (C-Term)

N° du produit ABIN2777171

L’anticorps anti-Aurora A Polyclonal Lapin est utilisé pour la détection de Aurora A dans des échantillons de Humain, Boeuf (Vache) et Mouton. Il a été validé pour WB et IHC.

Aperçu rapide pour Aurora A anticorps (C-Term) (ABIN2777171)

Antigène: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivité: Humain, Boeuf (Vache), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Aurora A anticorps

Épitope: C-Term

Fonction: AURKA Antibody - C-terminal region

Séquence: ARDLISRLLK HNPSQRPMLR EVLEHPWITA NSSKPSNCQN KESASKQS

Homologie: Cow: 80%, Human: 100%, Sheep: 80%

Attributs du produit: This is a rabbit polyclonal antibody against AURKA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human AURKA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30876-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Aurora A

Antigène: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Autre désignation: AURKA

Sujet:

Background Information: AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Gene Name: Aurora kinase A

Alternative Symbols: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, PPP1R47

Protein Name: Aurora kinase A

Poids moléculaire: 46kDa

ID gène: 6790

NCBI Accession: NP_003591

UniProt: O14965

Pathways: Cycle Cellulaire, Asymmetric Protein Localization