Progesterone Receptor anticorps (N-Term)

N° du produit ABIN2777173

L’anticorps anti-Progesterone Receptor Polyclonal Lapin est utilisé pour la détection de Progesterone Receptor dans des échantillons de Humain, Rat et Lapin. Il a été validé pour WB.

Aperçu rapide pour Progesterone Receptor anticorps (N-Term) (ABIN2777173)

Antigène: Progesterone Receptor (PGR)

Reactivité: Humain, Rat, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Progesterone Receptor est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Progesterone Receptor anticorps

Épitope: N-Term

Fonction: PGR Antibody - N-terminal region

Séquence: LPRGLSPARQ LLLPASESPH WSGAPVKPSP QAAAVEVEEE DGSESEESAG

Homologie: Human: 100%, Rabbit: 91%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against PR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human PGR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30886-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Progesterone Receptor

Antigène: Progesterone Receptor (PGR)

Autre désignation: PGR

Sujet:

Background Information: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Gene Name: progesterone receptor

Alternative Symbols: PR, NR3C3

Protein Name: progesterone receptor

Poids moléculaire: 75kDa

ID gène: 5241

NCBI Accession: NP_000917

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration