ISL1 anticorps (C-Term)

N° du produit ABIN2777250

Cet anticorps Lapin Polyclonal détecte spécifiquement ISL1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Lapin, Cheval et Mouton.

Aperçu rapide pour ISL1 anticorps (C-Term) (ABIN2777250)

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Lapin, Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISL1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ISL1 anticorps

Épitope: C-Term

Séquence: IMMKQLQQQQ PNDKTNIQGM TGTPMVAASP ERHDGGLQAN PVEVQSYQPP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ISL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ISL1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ISL1

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Autre désignation: ISL1

Sujet: ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation.
Alias Symbols: ISLET1, Isl-1
Protein Interaction Partner: ZNF511, KDM1A, RELA, SMAD3, CDKN2B, CDK6, APP, COPS5, SSBP4, LHX4, LDB2, ISL2, PECR, LDB1, LHX1, LHX3, LMX1A, RLIM, LMO2, ESR1, NR2F1, ISL1,
Protein Size: 349

Poids moléculaire: 39 kDa

ID gène: 3670

NCBI Accession: NM_002202, NP_002193

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding