CDK7 anticorps (N-Term)

N° du produit ABIN2777258

Cet anticorps Lapin Polyclonal détecte spécifiquement CDK7 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour CDK7 anticorps (N-Term) (ABIN2777258)

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDK7 anticorps

Épitope: N-Term

Séquence: VKSRAKRYEK LDFLGEGQFA TVYKARDKNT NQIVAIKKIK LGHRSEAKDG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CDK7

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDK7

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Autre désignation: CDK7

Sujet: CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Alias Symbols: CAK1, CDKN7, HCAK, MO15, STK1, p39MO15
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, GTF2H4, GTF2H3, GTF2H2, GTF2H1, ERCC5, ERCC3, ERCC2, CDK7, CCNH, ATP2B4, A2M, GTF2H5, SRPK2, SRPK1, MNAT1, TP53, CDK2, CTD, MBP, CDK1, CCNB1, CCNA2, Dlg4, UVSSA, HSP90AA1, HSD17B4, HLA-DQA1, SUPT5H, POLR2A, GTF2E2, GTF2E1, CDK9, APP
Protein Size: 346

Poids moléculaire: 39 kDa

ID gène: 1022

NCBI Accession: NM_001799, NP_001790

UniProt: P50613

Pathways: Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase