Prohibitin anticorps (C-Term)

N° du produit ABIN2777606

L’anticorps Lapin Polyclonal anti-Prohibitin a été validé pour WB et IHC. Il convient pour détecter Prohibitin dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Lapin, Cobaye, Boeuf (Vache), Chien et Cheval.

Aperçu rapide pour Prohibitin anticorps (C-Term) (ABIN2777606)

Antigène: Prohibitin (PHB)

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Lapin, Cobaye, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Prohibitin anticorps

Épitope: C-Term

Séquence: AEQQKKAAII SAEGDSKAAE LIANSLATAG DGLIELRKLE AAEDIAYQLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PHB. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PHB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 272 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Prohibitin

Antigène: Prohibitin (PHB)

Autre désignation: PHB

Sujet: Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Alias Symbols: PHB1
Protein Interaction Partner: FUS, HUWE1, SUMO2, SPRTN, STAU1, MDM2, SUZ12, EED, RNF2, PARP1, NAP1L1, COX6C, LONRF3, FBXO6, ADRB2, HDAC5, RAF1, KRAS, RAPH1, IPO11, SMG5, YWHAZ, YWHAB, VDAC2, RPS4X, RPL7, PRKCD, PLEC, NPM1, LMNA, IGHG1, HSP90AB1, GTF3C1, DBN1, COL9A2, CAPZA1, SLC25A5,
Protein Size: 272

Poids moléculaire: 30 kDa

ID gène: 5245

NCBI Accession: NM_002634, NP_002625

UniProt: P35232

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling