MYST2 anticorps (N-Term)
Aperçu rapide pour MYST2 anticorps (N-Term) (ABIN2777626)
Antigène
Voir toutes MYST2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Fonction
- MYST2 Antibody - N-terminal region
-
Séquence
- MPRRKRNAGS SSDGTEDSDF STDLEHTDSS ESDGTSRRSA RVTRSSARLS
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
-
Attributs du produit
- This is a rabbit polyclonal antibody against MYST2. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human MYST2
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32842-100UG
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- prevent freeze-thaw cycles
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- MYST2 (MYST Histone Acetyltransferase 2 (MYST2))
-
Autre désignation
- MYST2
-
Sujet
-
Background Information: MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.
Gene Name: K(lysine) acetyltransferase 7
Alternative Symbols: HBO1, HBOA, MYST2, ZC2HC7
Protein Name: Histone acetyltransferase KAT7
-
Poids moléculaire
- 71kDa
-
ID gène
- 11143
-
NCBI Accession
- NP_008998
-
UniProt
- O95251
Antigène
-