POLE3 anticorps (N-Term)

N° du produit ABIN2777723

Détail du produit anti-POLE3 anticorps

Antigène: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Poisson zèbre (Danio rerio), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLE3 est non-conjugé

Application: Western Blotting (WB)

Séquence: MAERPEDLNL PNAVITRIIK EALPDGVNIS KEARSAISRA ASVFVLYATS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against POLE3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human POLE3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 147 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur POLE3

Antigène: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Autre désignation: POLE3 (POLE3 Produits)

Sujet: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Alias Symbols: p17, YBL1, CHRAC17, CHARAC17
Protein Interaction Partner: CHRAC1, DRAP1, DR1, UBC, NANS, ANXA6, gag-pol, POLE4, CPSF2, POLE, APP, YEATS2, POLE2, Cebpb, SUMO2, XRCC5, BAZ1A, SMARCA5, RAD17,
Protein Size: 147

Poids moléculaire: 17 kDa

ID gène: 54107

NCBI Accession: NM_017443, NP_059139

UniProt: Q9NRF9

Pathways: Réparation de l'ADN