ARID4A anticorps (C-Term)

N° du produit ABIN2777742

Cet anticorps Lapin Polyclonal détecte spécifiquement ARID4A dans WB. Il présente une réactivité envers Humain, Chien, Boeuf (Vache), Cobaye, Cheval, Souris, Porc, Lapin et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour ARID4A anticorps (C-Term) (ABIN2777742)

Antigène: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Reactivité: Humain, Chien, Boeuf (Vache), Cobaye, Cheval, Souris, Porc, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARID4A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ARID4A anticorps

Épitope: C-Term

Séquence: NSSKCTPVKH LNVSKPQKLA RSPARISPHI KDGEKDKHRE KHPNSSPRTY

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ARID4A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ARID4A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1257 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ARID4A (ABIN2777742)

Kondou, Kawai, Tachikawa, Kimoto, Yamagata, Koinuma, Yamazaki, Nakayama, Mushiake, Ozono, Michigami: "Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development." dans: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 43, Issue 11, pp. 1211-23, (2014) (PubMed).

Détails sur ARID4A

Antigène: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Autre désignation: ARID4A

Sujet: ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.
Alias Symbols: RBP1, RBBP1, RBP-1, RBBP-1
Protein Interaction Partner: SUMO2, SUMO1, HDAC1, BRMS1, HIST2H3C, HIST4H4, UBC, CDK2, CDK1, CCNE1, CCNB1, CCNA2, CCND1, CDK4, SIN3A, SAP30, RB1, SIN3B, RBBP7, RBBP4, ARID4B, HDAC3, EID1, HDAC2, ING2, RBL1,
Protein Size: 1257

Poids moléculaire: 143 kDa

ID gène: 5926

NCBI Accession: NM_002892, NP_002883

UniProt: P29374