BAF53A anticorps (N-Term)

N° du produit ABIN2777881

Détail du produit anti-BAF53A anticorps

Antigène: BAF53A (Actin-Like 6A (BAF53A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAF53A est non-conjugé

Application: Western Blotting (WB)

Séquence: VDFPTAIGMV VERDDGSTLM EIDGDKGKQG GPTYYIDTNA LRVPRENMEA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ACTL6A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ACTL6A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 429 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BAF53A

Antigène: BAF53A (Actin-Like 6A (BAF53A))

Autre désignation: ACTL6A (BAF53A Produits)

Synonymes: anticorps ACTL6, anticorps ARPN-BETA, anticorps Arp4, anticorps BAF53A, anticorps INO80K, anticorps 2810432C06Rik, anticorps AI851094, anticorps ARP4, anticorps Actl6, anticorps Baf53a, anticorps C79802, anticorps baf53a, anticorps fb52e06, anticorps fl26e12, anticorps chunp6900, anticorps wu:fb52e06, anticorps wu:fl26e12, anticorps actl6, anticorps MGC75671, anticorps RGD1307747, anticorps ACTL6A, anticorps ATARP4, anticorps F15H18.8, anticorps F15H18_8, anticorps actin-related protein 4, anticorps Actin-like protein 4, anticorps CaO19.5623, anticorps actin, anticorps actl6a, anticorps actl6a.L, anticorps arp4, anticorps arpn-beta, anticorps ino80k, anticorps actin like 6A, anticorps actin-like 6A, anticorps actin-related protein 4, anticorps Arp4p, anticorps actin like 6A S homeolog, anticorps ACTL6A, anticorps Actl6a, anticorps actl6a, anticorps ARP4, anticorps actl6a.S

Sujet: This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Alias Symbols: ACTL6, BAF53A, MGC5382, Arp4, INO80K, ARPN-BETA
Protein Interaction Partner: UBC, BMI1, HECW2, FBXO6, HDAC2, CBX5, UCHL5, ARID1B, RUVBL1, TRRAP, ARID1A, SMARCE1, SMARCC2, SMARCC1, SMARCA4, SMARCA2, UBD, GRB2, INO80E, CAND1, CUL3, CDK9, CDK2, H2AFZ, TP53, UL27, SMARCD1, HDGF, SOX2, SMARCAD1, KAT5, PBRM1, Bcl7b, INO80C, ACTR8, INO80
Protein Size: 429

Poids moléculaire: 47 kDa

ID gène: 86

NCBI Accession: NM_004301, NP_004292

UniProt: O96019

Pathways: Chromatin Binding, Photoperiodism