WHSC1 anticorps (N-Term)

N° du produit ABIN2777965

Cité dans 1 publication. Cet anticorps anti-WHSC1 Polyclonal Lapin (ABIN2777965) détecte spécifiquement WHSC1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour WHSC1 anticorps (N-Term) (ABIN2777965)

Antigène: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WHSC1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-WHSC1 anticorps

Épitope: N-Term

Fonction: NSD2 Antibody - N-terminal region

Séquence: KYNVGDLVWS KVSGYPWWPC MVSADPLLHS YTKLKGQKKS ARQYHVQFFG

Homologie: Dog: 93%, Guinea Pig: 88%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 76%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against WHSC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human WHSC1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8115936

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-WHSC1 (ABIN2777965)

Li, Yin, Okamoto, Mushlin, Balgley, Lee, Yuan, Ikejiri, Glasker, Vortmeyer, Oldfield, Weil, Zhuang: "Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas." dans: Neuro-oncology, Vol. 10, Issue 1, pp. 45-51, (2008) (PubMed).

Détails sur WHSC1

Antigène: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Autre désignation: NSD2

Sujet:

Background Information: This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4,14)(p16.3,q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Gene Name: nuclear receptor binding SET domain protein 2

Alternative Symbols: WHS, TRX5, KMT3F, KMT3G, MMSET, WHSC1, REIIBP

Protein Name: histone-lysine N-methyltransferase NSD2

Poids moléculaire: 88kDa

ID gène: 7468

NCBI Accession: NP_055734

UniProt: O96031

Pathways: SARS-CoV-2 Protein Interactome