MLL4 anticorps (N-Term)

N° du produit ABIN2778080

Détail du produit anti-MLL4 anticorps

Antigène: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Saccharomyces cerevisiae, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLL4 est non-conjugé

Application: Western Blotting (WB)

Séquence: WAGPRVQRGR GRGRGRGWGP SRGCVPEEES SDGESDEEEF QGFHSDEDVA

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 92%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Yeast: 91%

Attributs du produit: This is a rabbit polyclonal antibody against MLL4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MLL4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 582 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MLL4

Antigène: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Autre désignation: MLL4 (MLL4 Produits)

Synonymes: anticorps HRX2, anticorps MLL1B, anticorps MLL2, anticorps MLL4, anticorps TRX2, anticorps WBP7, anticorps 2610014H22Rik, anticorps Mll2, anticorps Wbp7, anticorps mKIAA0304, anticorps ALR, anticorps BC032281, anticorps BC058659, anticorps C430014K11Rik, anticorps KMT2B, anticorps Mll4, anticorps RGD1308331, anticorps lysine methyltransferase 2B, anticorps lysine (K)-specific methyltransferase 2B, anticorps lysine (K)-specific methyltransferase 2D, anticorps KMT2B, anticorps Kmt2b, anticorps Kmt2d

Sujet: MLL4 a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. MLL4 is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer
Alias Symbols: HRX2, MLL2, TRX2, WBP7, MLL4
Protein Interaction Partner: UBC, SMAD3, ZNF512B, ATXN1, HIST2H3C, WDR5, ASH2L, RBBP5, SEPT8, RPP14, NREP, TSC22D1, TK1, SMN1, RAP1B, PIN1, GRB7, RCC1, CDKN1A, ATP1B1, ANXA7, ANXA1, BCL6, WDR82, PAGR1, PAXIP1, NCOA6, SMARCB1, PRPF40A,
Protein Size: 582

Poids moléculaire: 64 kDa

ID gène: 9757

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, L'effet Warburg