MLL4 anticorps (AA 1060-1140)

N° du produit ABIN8122090

Cet anticorps anti-MLL4 Polyclonal Lapin (ABIN8122090) détecte spécifiquement MLL4 dans IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MLL4 anticorps (AA 1060-1140) (ABIN8122090)

Antigène: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLL4 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MLL4 anticorps

Épitope: AA 1060-1140

Fonction: MLL4 Antibody

Specificité: MLL4 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 1060-1140

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-300. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MLL4

Antigène: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Autre désignation: MLL4

Sujet:

Background: This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008],

Gene Name: WBP7 HRX2 KIAA0304 KMT2B MLL2 MLL4 TRX2

Protein Name: Histone-lysine N-methyltransferase MLL4 (EC 2.1.1.43) (Lysine N-methyltransferase 2B) (KMT2B) (Myeloid/lymphoid or mixed-lineage leukemia protein 4) (Trithorax homolog 2) (WW domain-binding protein 7) (WBP-7)

ID gène: 9757

UniProt: Q9UMN6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, L'effet Warburg