PARP2 anticorps (C-Term)

N° du produit ABIN2778111

Détail du produit anti-PARP2 anticorps

Antigène: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP2 est non-conjugé

Application: Western Blotting (WB)

Séquence: QCNELLEANP KAEGLLQGKH STKGLGKMAP SSAHFVTLNG STVPLGPASD

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PARP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARP2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PARP2

Antigène: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Autre désignation: PARP2 (PARP2 Produits)

Synonymes: anticorps ADPRT2, anticorps ADPRTL2, anticorps ADPRTL3, anticorps ARTD2, anticorps PARP-2, anticorps pADPRT-2, anticorps Adprt2, anticorps Adprtl2, anticorps Aspartl2, anticorps C78626, anticorps cb996, anticorps adprtl2, anticorps ADPRT-2, anticorps APP, anticorps ATPARP1, anticorps PARP1, anticorps POLY(ADP-RIBOSE) POLYMERASE, anticorps POLY(ADP-RIBOSE) POLYMERASE 1, anticorps PP, anticorps T14P8.19, anticorps T14P8_19, anticorps poly(ADP-ribose) polymerase, anticorps poly(ADP-ribose) polymerase 2, anticorps poly(ADP-ribose) polymerase 2, anticorps poly (ADP-ribose) polymerase family, member 2, anticorps poly (ADP-ribose) polymerase 2, anticorps poly(ADP-ribose) polymerase 2 S homeolog, anticorps poly(ADP-ribose) polymerase, anticorps PARP2, anticorps Parp2, anticorps parp2, anticorps parp2.S

Sujet: PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Alias Symbols: ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Protein Interaction Partner: UHRF1, Npm1, TFAP4, UBC, RNF146, H3F3A, CBX5, TRIM28, CHD1L, TNP2, HSPA2, BUB3, CASP8, XRCC1, PARP1, CENPB, CENPA,
Protein Size: 570

Poids moléculaire: 62 kDa

ID gène: 10038

NCBI Accession: NM_001042618, NP_001036083

Pathways: Réparation de l'ADN