PARP2 anticorps (C-Term)

N° du produit ABIN2778111

Cet anticorps anti-PARP2 Polyclonal Lapin (ABIN2778111) détecte spécifiquement PARP2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin et Cobaye.

Aperçu rapide pour PARP2 anticorps (C-Term) (ABIN2778111)

Antigène: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PARP2 anticorps

Épitope: C-Term

Séquence: QCNELLEANP KAEGLLQGKH STKGLGKMAP SSAHFVTLNG STVPLGPASD

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PARP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARP2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PARP2

Antigène: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Autre désignation: PARP2

Sujet: PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Alias Symbols: ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Protein Interaction Partner: UHRF1, Npm1, TFAP4, UBC, RNF146, H3F3A, CBX5, TRIM28, CHD1L, TNP2, HSPA2, BUB3, CASP8, XRCC1, PARP1, CENPB, CENPA,
Protein Size: 570

Poids moléculaire: 62 kDa

ID gène: 10038

NCBI Accession: NM_001042618, NP_001036083

Pathways: Réparation de l'ADN