RGS17 anticorps (C-Term)

N° du produit ABIN2778238

Cet anticorps anti-RGS17 Polyclonal Lapin (ABIN2778238) détecte spécifiquement RGS17 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour RGS17 anticorps (C-Term) (ABIN2778238)

Antigène: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS17 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RGS17 anticorps

Épitope: C-Term

Séquence: NRNLLDPNPH MYEDAQLQIY TLMHRDSFPR FLNSQIYKSF VESTAGSSSE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RGS17. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RGS17

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RGS17

Antigène: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Autre désignation: RGS17

Sujet: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alias Symbols: RGS-17, RGSZ2, hRGS17
Protein Interaction Partner: LCE3C, LCE2A, LCE4A, TBC1D16, DHX37, NUFIP2, PTGER3, OTX1, RPL10A, SMCP, HOXA1, GNAI3, GNAI1, AQP1, ADRB2, RABEP1, RBBP8, UBC, OSTM1,
Protein Size: 210

Poids moléculaire: 23 kDa

ID gène: 26575

NCBI Accession: NM_012419, NP_036551

UniProt: Q9UGC6

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling