COPS2 anticorps (N-Term)

N° du produit ABIN2778317

L’anticorps Lapin Polyclonal anti-COPS2 a été validé pour WB. Il convient pour détecter COPS2 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cheval, Cobaye, Lapin, Saccharomyces cerevisiae et Chévre.

Aperçu rapide pour COPS2 anticorps (N-Term) (ABIN2778317)

Antigène: COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cheval, Cobaye, Lapin, Saccharomyces cerevisiae, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-COPS2 anticorps

Épitope: N-Term

Séquence: MSDMEDDFMC DDEEDYDLEY SEDSNSEPNV DLENQYYNSK ALKEDDPKAA

Homologie: Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against COPS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human COPS2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 443 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur COPS2

Antigène: COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))

Autre désignation: COPS2

Sujet: COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/Ion ChannelSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
Alias Symbols: ALIEN, CSN2, SGN2, TRIP15
Protein Interaction Partner: UBC, GPS1, Map3k10, 5830415F09Rik, Taf1b, EP300, Crebbp, cul1, COPS7B, EPB41L1, COPS5, FBXW4, SENP8, vpr, IRF5, COPS4, COPS7A, COPS6, COPS8, COPS3, PMPCA, SEPHS1, EHBP1L1, SLAIN2, GAPVD1, PFKFB2, SEPT2, IRS2, GRK5, DDB2, LRR1, DCAF11, DDA1, RFWD2, DCAF8,
Protein Size: 443

Poids moléculaire: 52 kDa

ID gène: 9318

NCBI Accession: NM_004236, NP_004227

UniProt: P61201

Pathways: Cycle Cellulaire