CDC25A anticorps (N-Term)

N° du produit ABIN2778347

Cet anticorps Lapin Polyclonal détecte spécifiquement CDC25A dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin et Cobaye.

Aperçu rapide pour CDC25A anticorps (N-Term) (ABIN2778347)

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDC25A anticorps

Épitope: N-Term

Séquence: QLQGLGSDYE QPLEVKNNSN LQRMGSSEST DSGFCLDSPG PLDSKENLEN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CDC25A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CDC25A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 524 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDC25A

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Autre désignation: CDC25A

Sujet: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CDC25A2
Protein Interaction Partner: ANAPC11, FZR1, FBXW11, BTRC, CUL1, SKP1, VCP, UBC, NPLOC4, YWHAQ, SCYL1, CAMK1D, POLR1D, FGF21, CHEK2, CCNI, MCM3AP, VAMP8, CUL3, XPO1, SOX5, PEX19, NFYA, NFKBIB, MTAP, SMAD3, LMO2, IL3RA, HLA-C, FTH1, EEF1A1, DMD, CHEK1, APP, TRIB3, CSNK1A1, CDK2, FAM193
Protein Size: 524

Poids moléculaire: 59 kDa

ID gène: 993

NCBI Accession: NM_001789, NP_001780

UniProt: P30304

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase