RAE1 anticorps (C-Term)

N° du produit ABIN2778733

Cet anticorps Lapin Polyclonal détecte spécifiquement RAE1 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval, Lapin et Cobaye.

Aperçu rapide pour RAE1 anticorps (C-Term) (ABIN2778733)

Antigène: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAE1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RAE1 anticorps

Épitope: C-Term

Séquence: EQLDQPISAC CFNHNGNIFA YASSYDWSKG HEFYNPQKKN YIFLRNAAEE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against RAE1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RAE1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 368 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAE1

Antigène: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Autre désignation: RAE1

Sujet: RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: MIG14, MRNP41, Mnrp41, dJ481F12.3, dJ800J21.1
Protein Interaction Partner: TP53, CDC37, DGCR8, YAP1, STK3, EEF2K, SOX2, HNRNPUL1, YWHAQ, UBC, FN1, ZC3HAV1, UBD, DDX39B, NUP98, MAP2, NUMA1, RNA28S5, RNA18S5, LSM14A, IGF2BP3, NXF1, TACC3, DYNLL1, KHSRP, KPNB1, ILF3, COPS6, CUL1, CUL3, Nup214, Nup188, KAT2A, PTTG1, POLR3H, FAM122B,
Protein Size: 368

Poids moléculaire: 40 kDa

ID gène: 8480

NCBI Accession: NM_001015885, NP_001015885

UniProt: P78406

Pathways: SARS-CoV-2 Protein Interactome