RAE1 anticorps (C-Term)

N° du produit ABIN2778733

Détail du produit anti-RAE1 anticorps

Antigène: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAE1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: EQLDQPISAC CFNHNGNIFA YASSYDWSKG HEFYNPQKKN YIFLRNAAEE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against RAE1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RAE1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 368 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAE1

Antigène: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Autre désignation: RAE1 (RAE1 Produits)

Synonymes: anticorps gle2, anticorps mig14, anticorps mnrp41, anticorps mrnp41, anticorps MRNP41, anticorps zgc:56449, anticorps zgc:77723, anticorps 3230401I12Rik, anticorps 41, anticorps D2Ertd342e, anticorps MNRP, anticorps MNRP41, anticorps MIG14, anticorps Mnrp41, anticorps dJ481F12.3, anticorps dJ800J21.1, anticorps ribonucleic acid export 1, anticorps RAE1 RNA export 1 homolog, anticorps ribonucleic acid export 1 L homeolog, anticorps rae1, anticorps LOC664096, anticorps RAE1, anticorps rae1.L, anticorps Rae1

Sujet: RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: MIG14, MRNP41, Mnrp41, dJ481F12.3, dJ800J21.1
Protein Interaction Partner: TP53, CDC37, DGCR8, YAP1, STK3, EEF2K, SOX2, HNRNPUL1, YWHAQ, UBC, FN1, ZC3HAV1, UBD, DDX39B, NUP98, MAP2, NUMA1, RNA28S5, RNA18S5, LSM14A, IGF2BP3, NXF1, TACC3, DYNLL1, KHSRP, KPNB1, ILF3, COPS6, CUL1, CUL3, Nup214, Nup188, KAT2A, PTTG1, POLR3H, FAM122B,
Protein Size: 368

Poids moléculaire: 40 kDa

ID gène: 8480

NCBI Accession: NM_001015885, NP_001015885

UniProt: P78406

Pathways: SARS-CoV-2 Protein Interactome