AARS anticorps (C-Term)

N° du produit ABIN2778778

Cet anticorps anti-AARS est un anticorps Lapin Polyclonal détectant AARS dans WB et IHC. Adapté pour Humain, Rat, Souris, Cobaye, Cheval, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio) et Chien.

Aperçu rapide pour AARS anticorps (C-Term) (ABIN2778778)

Antigène: AARS (Alanyl tRNA Synthetase (AARS))

Reactivité: Humain, Rat, Souris, Cobaye, Cheval, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AARS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-AARS anticorps

Épitope: C-Term

Séquence: VTGAEAQKAL RKAESLKKCL SVMEAKVKAQ TAPNKDVQRE IADLGEALAT

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against AARS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human AARS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 968 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AARS

Antigène: AARS (Alanyl tRNA Synthetase (AARS))

Autre désignation: AARS

Sujet: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Alias Symbols: CMT2N
Protein Interaction Partner: ISG15, UBC, SUMO2, SUMO1, NEDD8, TPD52, STAT5B, SRP9, PPP2R5E, METTL1, HSF1, CALU, DPP9, NIF3L1, ANKMY2, DPP8, IPO11, EEF2K, CACYBP, ARPC1B, SAE1, TOM1L1, EIF4A3, WARS, TPD52L2, UBD, VCAM1, ITGA4, HSP90AB1, HSP90AA1, FN1, NSUN2, LARS, FARSB, UBA1, QARS, N
Protein Size: 968

Poids moléculaire: 107 kDa

ID gène: 16

NCBI Accession: NM_001605, NP_001596

UniProt: P49588