HNRNPF anticorps (C-Term)

N° du produit ABIN2778920

Cet anticorps Lapin Polyclonal détecte spécifiquement HNRNPF dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien et Cheval.Il a été cité dans 1 publication.

Aperçu rapide pour HNRNPF anticorps (C-Term) (ABIN2778920)

Antigène: HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HNRNPF anticorps

Épitope: C-Term

Fonction: HNRPF Antibody - C-terminal region

Séquence: LNSTTGASNG AYSSQVMQGM GVSAAQATYS GLESQSVSGC YGAGYSGQNS

Homologie: Cow: 91%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HNRPF. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPF

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40565-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HNRNPF (ABIN2778920)

White, Gonsior, Bauer, Krämer-Albers, Luhmann, Trotter: "Heterogeneous nuclear ribonucleoprotein (hnRNP) F is a novel component of oligodendroglial RNA transport granules contributing to regulation of myelin basic protein (MBP) synthesis." dans: The Journal of biological chemistry, Vol. 287, Issue 3, pp. 1742-54, (2012) (PubMed).

Détails sur HNRNPF

Antigène: HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))

Autre désignation: HNRPF

Sujet:

Background Information: HNRPF belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH.

Gene Name: Heterogeneous nuclear ribonucleoprotein F

Alternative Symbols: HNRPF, mcs94-1, OK/SW-cl.23

Protein Name: Heterogeneous nuclear ribonucleoprotein F

Poids moléculaire: 46kDa

ID gène: 3185

NCBI Accession: NP_004957

UniProt: P52597