SF3B4 anticorps (N-Term)

N° du produit ABIN2778952

L’anticorps Lapin Polyclonal anti-SF3B4 a été validé pour WB et IHC. Il convient pour détecter SF3B4 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cobaye, Lapin, Saccharomyces cerevisiae, Cheval et Chévre.

Aperçu rapide pour SF3B4 anticorps (N-Term) (ABIN2778952)

Antigène: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cobaye, Lapin, Saccharomyces cerevisiae, Cheval, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SF3B4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SF3B4 anticorps

Épitope: N-Term

Séquence: QDATVYVGGL DEKVSEPLLW ELFLQAGPVV NTHMPKDRVT GQHQGYGFVE

Homologie: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SF3B4. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 424 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SF3B4

Antigène: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Autre désignation: SF3B4

Sujet: SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Alias Symbols: Hsh49, SAP49, SF3b49
Protein Interaction Partner: NCK2, METTL17, ZCCHC10, UBASH3A, NUB1, HSPB7, PPP1R16B, SS18L1, HNRNPUL1, SF3B2, BAIAP2, SEC24D, FAM115A, RBM39, BAG3, CWF19L2, MAPK9, FUS, FRK, FKBP1A, STAU1, UBC, SUMO1, SUZ12, RNF2, PRPF40A, WBP4, APBB1, SRPK3, DDX42, PRPF8, CHERP, DDX17, BCAS2, EFTUD2
Protein Size: 424

Poids moléculaire: 47 kDa

ID gène: 10262

NCBI Accession: NM_005850, NP_005841

UniProt: Q15427