FADD anticorps (C-Term)

N° du produit ABIN309589

Cet anticorps Lapin Polyclonal détecte spécifiquement FADD dans WB. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour FADD anticorps (C-Term) (ABIN309589)

Antigène: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FADD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FADD anticorps

Épitope: C-Term

Séquence: ASVAGLVKAL RTCRLNLVAD LVEEAQESVS KSENMSPVLR DSTVSSSETP

Homologie: Mouse: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Fadd. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of mouse FADD

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 205 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FADD

Antigène: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Autre désignation: FADD

Sujet: Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Alias Symbols: Mort1/FADD
Protein Interaction Partner: Atg16l1, Atg7, Atg12, Map1lc3a, Ripk1, Casp8, Atg5, Fas, Pidd1, Cflar, Tnf, Nol3,
Protein Size: 205

Poids moléculaire: 23 kDa

ID gène: 14082

NCBI Accession: NM_010175, NP_034305

UniProt: Q61160

Pathways: Apoptose, Signalisation TLR, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades