SUMO1 anticorps (N-Term)

N° du produit ABIN2779357

Détail du produit anti-SUMO1 anticorps

Antigène: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUMO1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DQEAKPSTED LGDKKEGEYI KLKVIGQDSS EIHFKVKMTT HLKKLKESYC

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Sumo1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 101 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SUMO1

Antigène: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Autre désignation: Sumo1 (SUMO1 Produits)

Synonymes: anticorps DAP1, anticorps GMP1, anticorps OFC10, anticorps PIC1, anticorps SENP2, anticorps SMT3, anticorps SMT3C, anticorps SMT3H3, anticorps UBL1, anticorps hm:zeh0670, anticorps wu:fb74c02, anticorps wu:fd12c02, anticorps zgc:65934, anticorps zgc:85634, anticorps SUMO1, anticorps dap1, anticorps gmp1, anticorps ofc10, anticorps pic1, anticorps senp2, anticorps smt3, anticorps smt3c, anticorps sumo-1, anticorps sumo1, anticorps ubl1, anticorps xsumo-1, anticorps xsumo1, anticorps ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1, anticorps ATSUMO1, anticorps F10M23.180, anticorps F10M23_180, anticorps SMALL UBIQUITIN-LIKE MODIFIER 1, anticorps SUM1, anticorps SUMO 1, anticorps small ubiquitin-like modifier 1, anticorps pigSUMO1, anticorps SENTRIN, anticorps SMTP3, anticorps SUMO-1, anticorps Smt3C, anticorps Ubl1, anticorps small ubiquitin-like modifier 1, anticorps small ubiquitin-like modifier 1 S homeolog, anticorps small ubiquitin-related protein 1, anticorps SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), anticorps SMT3 suppressor of mif two 3 homolog 1 (yeast), anticorps small ubiquitin-like modifier 1 L homeolog, anticorps Sumo1, anticorps SUMO1, anticorps sumo1, anticorps sumo1.S, anticorps sumo-1, anticorps sumo1.L

Sujet: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. It is involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. It may also regulate a network of genes involved in palate development.
Alias Symbols: GMP1, MGC103203, PIC1, SENTRIN, SMT3, SMT3H3, SMTP3, SUMO-1, Smt3C, Ubl1
Protein Interaction Partner: Pten, Stat1, Pml, Casp8ap2, Traf3, Pik3c3, Npm1, Mdm2, Ube2i, Trp53, Rangap1, Ranbp2, Mthfs, Sox2, Senp2, Rbbp7, Slc1a2, Uimc1, Nfatc2ip, Irf1, Irf8, Smad4, BCL11A, AXIN1, Myb, Pax6, Sept2, Daxx, Sf1, Sp3, Pou5f1, Hif1a, Nfkb2, Junb, Jun,
Protein Size: 101

Poids moléculaire: 11 kDa

ID gène: 22218

NCBI Accession: NM_009460, NP_033486

UniProt: P63166

Pathways: M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway