TLE1 anticorps (N-Term)

N° du produit ABIN2779588

L’anticorps Lapin Polyclonal anti-TLE1 a été validé pour WB. Il convient pour détecter TLE1 dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour TLE1 anticorps (N-Term) (ABIN2779588)

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TLE1 anticorps

Épitope: N-Term

Séquence: RNGPEFSNDI KKRKVDDKDS SHYDSDGDKS DDNLVVDVSN EDPSSPRASP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TLE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 770 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TLE1

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Autre désignation: TLE1

Sujet: TLE1 is a transcriptional corepressor that binds to a number of transcription factors. TLE1 inhibits NF-kappa-B-regulated gene expression and the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE1 has an unusual function as coactivator for ESRRG.
Alias Symbols: ESG, ESG1, GRG1
Protein Interaction Partner: TLE1, TCF3, TCF4, UBC, SS18, SSX2, HDAC1, EZH2, ATF2, APH1A, LEF1, TLX3, PROP1, HES1, TLX1, HHEX, FOXG1, ESRRG, EN1, tcf7l1a, NOD2, AES, HESX1, GSK3B, GRB7, NUDT21, DAZAP2, KIAA0408, TSC22D1, TK1, SMN1, RAP1B, GADD45A, CSNK2B, RCC1, CDKN1A, BID, BCL2L1, A
Protein Size: 770

Poids moléculaire: 83 kDa

ID gène: 7088

NCBI Accession: NM_005077, NP_005068

UniProt: Q04724

Pathways: Signalisation WNT, SARS-CoV-2 Protein Interactome