HIRA anticorps (Middle Region)
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- Antigène Voir toutes HIRA Anticorps
- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HIRA est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LRSRELESSS DSDEKVHLAK PSSLSKRKLE LEVETVEKKK KGRPRKDSRL
- Homologie
- Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 86%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Hira. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of mouse Hira
- Top Product
- Discover our top product HIRA Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1015 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
- Autre désignation
- Hira (HIRA Produits)
- Synonymes
- anticorps HIRA, anticorps wu:fb97b07, anticorps wu:fi43b08, anticorps si:ch211-188g24.3, anticorps AA138857, anticorps D16Ertd95e, anticorps N28177, anticorps Tuple1, anticorps DGCR1, anticorps TUP1, anticorps TUPLE1, anticorps dgcr1, anticorps hira-A, anticorps tup1, anticorps tuple1, anticorps homolog of histone chaperone HIRA, anticorps histone cell cycle regulator, anticorps histone cell cycle regulator a, anticorps protein HIRA, anticorps HIR histone cell cycle regulation defective homolog A (S. cerevisiae), anticorps HIRA, anticorps histone cell cycle regulator S homeolog, anticorps histone chaperone HIRA-like protein, anticorps Tuple1/HirA, anticorps HIRA, anticorps hira, anticorps LOC100052845, anticorps LOC100352472, anticorps LOC100407742, anticorps LOC100450459, anticorps LOC100467668, anticorps LOC100581135, anticorps LOC486424, anticorps Hira, anticorps LOC732736, anticorps hira.S
- Sujet
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Hira is required for the periodic repression of histone gene transcription during the cell cycle.Hira cooperates with ASF1A to promote replication-independent chromatin assembly.Hira is required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Alias Symbols: AA138857, D16Ertd95e, N28177, Tuple1
Protein Interaction Partner: Nanog, Creb3l4, Crem, Pou5f1, Hirip3, Pax7, Pax3, H3f3b,
Protein Size: 1015 - Poids moléculaire
- 112 kDa
- ID gène
- 15260
- NCBI Accession
- NM_010435, NP_034565
- UniProt
- Q61666
- Pathways
- Chromatin Binding
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