HIRA anticorps (Middle Region)

N° du produit ABIN2779934

L’anticorps anti-HIRA Polyclonal Lapin est utilisé pour la détection de HIRA dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval et Lapin. Il a été validé pour WB.

Aperçu rapide pour HIRA anticorps (Middle Region) (ABIN2779934)

Antigène: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIRA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HIRA anticorps

Épitope: Middle Region

Fonction: Hira Antibody - middle region

Séquence: LRSRELESSS DSDEKVHLAK PSSLSKRKLE LEVETVEKKK KGRPRKDSRL

Homologie: Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 86%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Hira. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of mouse Hira

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37054-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur HIRA

Antigène: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Autre désignation: Hira

Sujet:

Background Information: Hira is required for the periodic repression of histone gene transcription during the cell cycle.Hira cooperates with ASF1A to promote replication-independent chromatin assembly.Hira is required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Gene Name: Histone cell cycle regulation defective homolog A (S. cerevisiae)

Alternative Symbols: Tupl, N28177, Tuple1, Gm15797, AA138857, D16Ertd95, D16Ertd95e

Protein Name: Protein HIRA

Poids moléculaire: 112

ID gène: 15260

NCBI Accession: NP_034565

UniProt: Q61666

Pathways: Chromatin Binding