Glypican 3 anticorps (Middle Region)

N° du produit ABIN2780199

L’anticorps Lapin Polyclonal anti-Glypican 3 a été validé pour WB et IHC. Il convient pour détecter Glypican 3 dans des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval et Lapin. Il y a 1 publication disponible.

Aperçu rapide pour Glypican 3 anticorps (Middle Region) (ABIN2780199)

Antigène: Glypican 3 (GPC3)

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glypican 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Glypican 3 anticorps

Épitope: Middle Region

Séquence: FSTIHDSIQY VQKNAGKLTT TIGKLCAHSQ QRQYRSAYYP EDLFIDKKVL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GPC3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GPC3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 580 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Glypican 3 (ABIN2780199)

Bhave, Mars, Donthamsetty, Zhang, Tan, Luo, Bowen, Michalopoulos: "Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex." dans: The American journal of pathology, Vol. 183, Issue 1, pp. 153-9, (2013) (PubMed).

Détails sur Glypican 3

Antigène: Glypican 3 (GPC3)

Autre désignation: GPC3

Sujet: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome.
Alias Symbols: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2
Protein Interaction Partner: UBC, WNT3A, WNT7B, IGF2, FGF2,
Protein Size: 580

Poids moléculaire: 64 kDa

ID gène: 2719

NCBI Accession: NM_004484, NP_004475

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process