SIAH1 anticorps (C-Term)

N° du produit ABIN2780459

Détail du produit anti-SIAH1 anticorps

Antigène: SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIAH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LVLEKQEKYD GHQQFFAIVQ LIGTRKQAEN FAYRLELNGH RRRLTWEATP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SIAH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SIAH1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 282 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SIAH1

Antigène: SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

Autre désignation: SIAH1 (SIAH1 Produits)

Synonymes: anticorps SIAH, anticorps Siah1, anticorps Siah1a, anticorps id:ibd2635, anticorps zgc:56026, anticorps SIAH1A, anticorps siah, anticorps E3 ubiquitin-protein ligase Siah1, anticorps E3 ubiquitin-protein ligase siah-1, anticorps siah E3 ubiquitin protein ligase 1, anticorps siah E3 ubiquitin protein ligase 1 L homeolog, anticorps Tsp_03055, anticorps siah-1, anticorps Siah1, anticorps siah1, anticorps SIAH1, anticorps siah1.L

Sujet: SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterizedThis gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Alias Symbols: SIAH1A
Protein Interaction Partner: MX1, MAB21L1, KIFC3, KCNJ10, INHA, UBE2K, FLI1, EEF1D, PHC2, PHC1, CDC34, CAPG, BCL6, TRIM23, AQP1, PFKM, ZCCHC13, MTIF3, UPP2, MOB3C, SPATA4, PRR20A, HIST4H4, EXOC3-AS1, PTPMT1, RPS19BP1, SPATC1L, KATNAL1, TRIM7, GDPD5, ZBP1, KIAA1683, ARMC9, KIAA0319L,
Protein Size: 282

Poids moléculaire: 31 kDa

ID gène: 6477

NCBI Accession: NM_003031, NP_003022

UniProt: Q8IUQ4