SOX2 anticorps (N-Term)

N° du produit ABIN309867

Cet anticorps anti-SOX2 Polyclonal Lapin (ABIN309867) détecte spécifiquement SOX2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chévre, Boeuf (Vache), Porc et Poisson zèbre (Danio rerio).

Aperçu rapide pour SOX2 anticorps (N-Term) (ABIN309867)

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reactivité: Humain, Souris, Rat, Chévre, Boeuf (Vache), Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SOX2 anticorps

Épitope: N-Term

Séquence: AAGGNQKNSP DRVKRPMNAF MVWSRGQRRK MAQENPKMHN SEISKRLGAE

Homologie: Cow: 100%, Goat: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SOX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SOX2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 317 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: SOX2

Sujet: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Alias Symbols: ANOP3, MGC2413, MCOPS3
Protein Interaction Partner: SUMO1, DMAP1, TBX2, SETD7, FAM21A, FZR1, MMS19, MRPS35, ZNF462, LSM2, CCAR2, MIER1, ZDBF2, CHD8, EP400, TSHZ3, RANBP10, ZNF687, XPO5, INTS2, MTA3, CORO1B, CASC5, MRPS22, KCMF1, MEPCE, TRERF1, INTS9, PARVA, SCYL2, CHD7, ZCCHC8, SOX6, BRIX1, SAMD4B, GID8, C
Protein Size: 317

Poids moléculaire: 34 kDa

ID gène: 6657

NCBI Accession: NM_003106, NP_003097

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis