IRF7 anticorps (N-Term)

N° du produit ABIN2780566

Cet anticorps anti-IRF7 est un anticorps Lapin Polyclonal détectant IRF7 dans WB. Adapté pour Humain, Souris, Rat, Porc, Poisson zèbre (Danio rerio), Cheval, Boeuf (Vache) et Lapin.

Aperçu rapide pour IRF7 anticorps (N-Term) (ABIN2780566)

Antigène: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reactivité: Humain, Souris, Rat, Porc, Poisson zèbre (Danio rerio), Cheval, Boeuf (Vache), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IRF7 anticorps

Épitope: N-Term

Séquence: ISSGCYEGLQ WLDEARTCFR VPWKHFARKD LSEADARIFK AWAVARGRWP

Homologie: Cow: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 75%

Attributs du produit: This is a rabbit polyclonal antibody against IRF7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 164 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IRF7

Antigène: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Autre désignation: IRF7

Sujet: IRF7 is interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue.IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.
Alias Symbols: IRF-7H, IRF7A
Protein Interaction Partner: UBC, SUMO2, SUMO3, TRAF6, NMI, DEAF1, MAFB, SMAD4, SMAD3, SMAD2, vIRF-1, Dlg4, PIAS4, INSR, GCLM, ACADS, MAVS, IRF7, IRF3, IRAK1, TBK1, TRIM28, SUMO1, EP300, CREBBP, TNFAIP3, TRIM21, P4HA1, ARAF, Gbp4, HACE1, CCDC47, TRMT61B, PALD1, TRMT2A, LTN1, TLK2, IQ
Protein Size: 164

Poids moléculaire: 18 kDa

ID gène: 3665

NCBI Accession: NM_004031, NP_004022

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy