CREB3 anticorps (Middle Region)

N° du produit ABIN2780771

Cet anticorps Lapin Polyclonal détecte spécifiquement CREB3 dans WB. Il présente une réactivité envers Humain, Boeuf (Vache) et Chien et a été mentionné dans 1 publication.

Aperçu rapide pour CREB3 anticorps (Middle Region) (ABIN2780771)

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Reactivité: Humain, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREB3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CREB3 anticorps

Épitope: Middle Region

Séquence: PPLEWPFPDL FSEPLCRGPI LPLQANLTRK GGWLPTGSPS VILQDRYSG

Homologie: Cow: 80%, Dog: 80%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CREB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CREB3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 371 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CREB3 (ABIN2780771)

Mamdani, Alda, Grof, Young, Rouleau, Turecki: "Lithium response and genetic variation in the CREB family of genes." dans: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 500-4, (2008) (PubMed).

Détails sur CREB3

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Autre désignation: CREB3

Sujet: CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LUMAN, LZIP, MGC15333, MGC19782
Protein Interaction Partner: COPS5, HCFC1, JUN, CREB3L1, CREB3L3, CREB3, NFE2L3, NFE2L2, DDIT3, CEBPG, ATF4, ATF3, TTLL5, RRAS2, OS9, RABAC1, SQLE, BCAT2, CLP1, UBC, HDAC3, MALL, NFIL3, APPBP2, STX8, BNIP2, CCR1, EMD,
Protein Size: 371

Poids moléculaire: 41 kDa

ID gène: 10488

NCBI Accession: NM_006368, NP_006359

UniProt: O43889

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response