NCOA2 anticorps (N-Term)

N° du produit ABIN2780788

Il existe 1 publication pour ce produit. L’anticorps anti-NCOA2 Polyclonal Lapin est utilisé pour la détection de NCOA2 dans des échantillons de Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval et Porc. Il a été validé pour WB.

Aperçu rapide pour NCOA2 anticorps (N-Term) (ABIN2780788)

Antigène: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NCOA2 anticorps

Épitope: N-Term

Fonction: NCOA2 Antibody - N-terminal region

Séquence: MSGMGENTSD PSRAETRKRK ECPDQLGPSP KRNTEKRNRE QENKYIEELA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NCOA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NCOA2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38815-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-NCOA2 (ABIN2780788)

Strehl, Nebral, König, Harbott, Strobl, Ratei, Struski, Bielorai, Lessard, Zimmermann, Haas, Izraeli: "ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 4, pp. 977-83, (2008) (PubMed).

Détails sur NCOA2

Antigène: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Autre désignation: NCOA2

Sujet:

Background Information: NCOA2 is the transcriptional coactivator for steroid receptors and nuclear receptors. NCOA2 is the coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). NCOA2 is required with NCOA1 to control energy balance

Gene Name: Nuclear receptor coactivator 2

Alternative Symbols: SRC2, TIF2, GRIP1, KAT13C, NCoA-2, bHLHe75

Protein Name: Nuclear receptor coactivator 2

Poids moléculaire: 159kDa

ID gène: 10499

NCBI Accession: NP_006531

UniProt: Q15596

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling