TAP1 anticorps (Middle Region)
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- Antigène Voir toutes TAP1 Anticorps
- TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TAP1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- LVTFVLYQMQ FTQAVEVLLS IYPRVQKAVG SSEKIFEYLD RTPRCPPSGL
- Homologie
- Cow: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 83%
- Attributs du produit
- This is a rabbit polyclonal antibody against TAP1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TAP1
- Top Product
- Discover our top product TAP1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 808 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))
- Autre désignation
- TAP1 (TAP1 Produits)
- Synonymes
- anticorps ABC17, anticorps ABCB2, anticorps APT1, anticorps D6S114E, anticorps PSF-1, anticorps PSF1, anticorps RING4, anticorps TAP1*0102N, anticorps TAP1N, anticorps abc17, anticorps abcb2, anticorps apt1, anticorps psf1, anticorps ring4, anticorps tap1a, anticorps tap1n, anticorps Abcb2, anticorps Ham-1, anticorps Ham1, anticorps MTP1, anticorps TAP, anticorps Tap-1, anticorps Y3, anticorps Cim, anticorps transporter 1, ATP binding cassette subfamily B member, anticorps transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) L homeolog, anticorps transporter 1, ATP-binding cassette, sub-family B (MDR/TAP), anticorps TAP1, anticorps tap1.L, anticorps Tap1
- Sujet
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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). TAP1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. TAP1 is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ABC17, ABCB2, APT1, D6S114E, FLJ26666, FLJ41500, PSF1, RING4, TAP1*0102N, TAP1N, PSF-1
Protein Interaction Partner: UBC, MUL1, TDP2, SFXN1, GADD45GIP1, MRPL40, MCAT, SRSF3, SDHA, ABCD3, CYC1, PSMB8, TAPBP, TAP2, HLA-A, PDIA3, CALR, B2M, PDIA2, KRTAP4-12, MDFI, PSMB5, HLA-F, HLA-G, ESR1, COPG1, COPB1,
Protein Size: 808 - Poids moléculaire
- 87 kDa
- ID gène
- 6890
- NCBI Accession
- NM_000593, NP_000584
- UniProt
- Q03518
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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