ChT anticorps (C-Term)

N° du produit ABIN2781677

Cet anticorps anti-ChT Polyclonal Lapin (ABIN2781677) détecte spécifiquement ChT dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien et Cheval.

Aperçu rapide pour ChT anticorps (C-Term) (ABIN2781677)

Antigène: ChT (High Affinity Choline Transporter (ChT))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ChT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ChT anticorps

Épitope: C-Term

Fonction: SLC5A7 Antibody - C-terminal region

Séquence: ILVKNENIKL DELALVKPRQ SMTLSSTFTN KEAFLDVDSS PEGSGTEDNL

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SLC5A7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC5A7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44025-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ChT

Antigène: ChT (High Affinity Choline Transporter (ChT))

Autre désignation: SLC5A7

Sujet:

Background Information: This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.

Gene Name: solute carrier family 5 (sodium/choline cotransporter), member 7

Alternative Symbols: CHT, CHT1, CMS20, HMN7A

Protein Name: high affinity choline transporter 1

Poids moléculaire: 63 kDa

ID gène: 60482

NCBI Accession: NP_001291934

UniProt: Q9GZV3