ChT anticorps (C-Term)

N° du produit ABIN2781677

Détail du produit anti-ChT anticorps

Antigène: ChT (High Affinity Choline Transporter (ChT))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ChT est non-conjugé

Application: Western Blotting (WB)

Séquence: ILVKNENIKL DELALVKPRQ SMTLSSTFTN KEAFLDVDSS PEGSGTEDNL

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SLC5A7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC5A7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ChT

Antigène: ChT (High Affinity Choline Transporter (ChT))

Autre désignation: SLC5A7 (ChT Produits)

Synonymes: anticorps CHT, anticorps CHT1, anticorps HMN7A, anticorps hCHT, anticorps Cht1, anticorps solute carrier family 5 member 7, anticorps solute carrier family 5 (choline transporter), member 7, anticorps SLC5A7, anticorps Slc5a7

Sujet: This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.
Alias Symbols: CHT, CHT1, HMN7A
Protein Size: 475

Poids moléculaire: 52 kDa

ID gène: 60482

NCBI Accession: NM_001305005, NP_001291934

UniProt: Q9GZV3