SLC39A4 anticorps (N-Term)

N° du produit ABIN405621

Cité dans 1 publication. Cet anticorps anti-SLC39A4 Polyclonal Lapin (ABIN405621) détecte spécifiquement SLC39A4 dans WB. L’anticorps est réactif avec des échantillons de Humain, Lapin et Boeuf (Vache).

Aperçu rapide pour SLC39A4 anticorps (N-Term) (ABIN405621)

Antigène: SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))

Reactivité: Humain, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC39A4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SLC39A4 anticorps

Épitope: N-Term

Séquence: ASLVSLELGL LLAVLVVTAT ASPPAGLLSL LTSGQGALDQ EALGGLLNTL

Homologie: Cow: 86%, Human: 100%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SLC39A4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC39A4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 647 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SLC39A4 (ABIN405621)

Antala, Ovchinnikov, Kamisetty, Baker, Dempski: "Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4." dans: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17796-805, (2015) (PubMed).

Détails sur SLC39A4

Antigène: SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))

Autre désignation: SLC39A4

Sujet: SLC39A4 is a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in the gene encoding SLC39A4 result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc.This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AEZ, FLJ20327, MGC74741, ZIP4, AWMS2
Protein Interaction Partner: UBC,
Protein Size: 647

Poids moléculaire: 68 kDa

ID gène: 55630

NCBI Accession: NM_130849, NP_570901

UniProt: Q6P5W5

Pathways: Transition Metal Ion Homeostasis, Autophagy