NEU1 anticorps (Middle Region)
Aperçu rapide pour NEU1 anticorps (Middle Region) (ABIN2781801)
Antigène
Voir toutes NEU1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- VWSKDDGVSW STPRNLSLDI GTEVFAPGPG SGIQKQREPR KGRLIVCGHG
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Homologie
- Cow: 100%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against NEU1. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human NEU1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 415 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
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Autre désignation
- NEU1
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Sujet
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NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.
Alias Symbols: NEU, SIAL1, NANH
Protein Interaction Partner: FBXO6, JUNB, LIG4, KCNA4, KCNA2, UBC, HDAC5, CTSA, GLB1, EEF1A1, GALNS,
Protein Size: 415 -
Poids moléculaire
- 45 kDa
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ID gène
- 4758
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NCBI Accession
- NM_000434, NP_000425
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UniProt
- Q99519
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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