Derlin-3 anticorps (Middle Region)

N° du produit ABIN2781868

L’anticorps anti-Derlin-3 Polyclonal Lapin est utilisé pour la détection de Derlin-3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval et Chévre. Il a été validé pour WB.

Aperçu rapide pour Derlin-3 anticorps (Middle Region) (ABIN2781868)

Antigène: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Derlin-3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Derlin-3 anticorps

Épitope: Middle Region

Fonction: DERL3 Antibody - middle region

Séquence: FFFNMLFVFR YCRMLEEGSF RGRTADFVFM FLFGGVLMTL LGLLGSLFFL

Homologie: Cow: 100%, Dog: 100%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DERL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DERL3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44442-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Derlin-3

Antigène: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Autre désignation: DERL3

Sujet:

Background Information: DERL3 belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene Name: Der1-like domain family, member 3

Alternative Symbols: IZP6, LLN2, C22orf14, derlin-3

Protein Name: Derlin-3

Poids moléculaire: 27kDa

ID gène: 91319

NCBI Accession: NP_001002862

UniProt: Q96Q80

Pathways: ER-Nucleus Signaling