PODXL anticorps (N-Term)

N° du produit ABIN2781991

L’anticorps anti-PODXL Polyclonal Lapin est utilisé pour la détection de PODXL dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour PODXL anticorps (N-Term) (ABIN2781991)

Antigène: PODXL (Podocalyxin-Like (PODXL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PODXL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PODXL anticorps

Épitope: N-Term

Fonction: PODXL Antibody - N-terminal region

Séquence: TTTVATSTAT AKPNTTSSQN GAEDTTNSGG KSSHSVTTDL TSTKAEHLTT

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PODXL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PODXL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44729-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PODXL

Antigène: PODXL (Podocalyxin-Like (PODXL))

Autre désignation: PODXL

Sujet:

Background Information: PODXL is a member of the sialomucin protein family. PODXL was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of PODXL include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Gene Name: Podocalyxin-like

Alternative Symbols: PC, PDX, PCLP, Gp200, gp135, PCLP-1, PODXL1

Protein Name: Podocalyxin

Poids moléculaire: 53kDa

ID gène: 5420

NCBI Accession: NP_005388

UniProt: Q53ER6

Pathways: Tube Formation