KREMEN1 anticorps (N-Term)

N° du produit ABIN2782050

Cet anticorps anti-KREMEN1 est un anticorps Lapin Polyclonal détectant KREMEN1 dans WB. Adapté pour Humain, Souris, Rat, Cobaye, Lapin, Boeuf (Vache), Chien, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour KREMEN1 anticorps (N-Term) (ABIN2782050)

Antigène: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KREMEN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KREMEN1 anticorps

Épitope: N-Term

Séquence: LKYPNGEGGL GEHNYCRNPD GDVSPWCYVA EHEDGVYWKY CEIPACQMPG

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against KREMEN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KREMEN1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 475 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KREMEN1

Antigène: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Autre désignation: KREMEN1

Sujet: KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Alias Symbols: FLJ31863, KREMEM1, KREMEN, KRM1
Protein Interaction Partner: DKK1,
Protein Size: 475

Poids moléculaire: 50 kDa

ID gène: 83999

NCBI Accession: NM_001039570, NP_001034659

UniProt: C1P671

Pathways: Signalisation WNT