FMO4 anticorps (N-Term)

N° du produit ABIN2782152

Cet anticorps Lapin Polyclonal détecte spécifiquement FMO4 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin et Chien.

Aperçu rapide pour FMO4 anticorps (N-Term) (ABIN2782152)

Antigène: FMO4 (Flavin Containing Monooxygenase 4 (FMO4))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FMO4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FMO4 anticorps

Épitope: N-Term

Fonction: FMO4 Antibody - N-terminal region

Séquence: MVCTGHFLNP HLPLEAFPGI HKFKGQILHS QEYKIPEGFQ GKRVLVIGLG

Homologie: Cow: 100%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FMO4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FMO4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45209-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FMO4

Antigène: FMO4 (Flavin Containing Monooxygenase 4 (FMO4))

Autre désignation: FMO4

Sujet:

Background Information: FMO4 belongs to the FMO family. Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.

Gene Name: Flavin containing monooxygenase 4

Alternative Symbols: FMO2

Protein Name: Dimethylaniline monooxygenase [N-oxide-forming] 4

Poids moléculaire: 63kDa

ID gène: 2329

NCBI Accession: NP_002013

UniProt: P31512