SMPD2 anticorps (N-Term)

N° du produit ABIN2782209

Détail du produit anti-SMPD2 anticorps

Antigène: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMPD2 est non-conjugé

Application: Western Blotting (WB)

Séquence: RQKLSPTYPA AHHFRSGIIG SGLCVFSKHP IQELTQHIYT LNGYPYMIHH

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 77%, Rabbit: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SMPD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SMPD2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 423 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SMPD2 (ABIN2782209)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Détails sur SMPD2

Antigène: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Autre désignation: SMPD2 (SMPD2 Produits)

Synonymes: anticorps SMPD2, anticorps NSMase, anticorps isc1, anticorps nsmase, anticorps nsmase1, anticorps AW108287, anticorps nSMase, anticorps nSMase1, anticorps ISC1, anticorps NSMASE, anticorps NSMASE1, anticorps sphingomyelin phosphodiesterase 2, anticorps sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase), anticorps sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase), anticorps sphingomyelin phosphodiesterase 2, neutral, anticorps SMPD2, anticorps smpd2a, anticorps smpd2, anticorps Smpd2

Sujet: SMPD2 converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
Alias Symbols: NSMASE, ISC1, NSMASE1
Protein Interaction Partner: UBC, PIK3CG,
Protein Size: 423

Poids moléculaire: 48 kDa

ID gène: 6610

NCBI Accession: NM_003080, NP_003071

UniProt: O60906

Pathways: Neurotrophin Signaling Pathway