HNF4A anticorps (Middle Region)

N° du produit ABIN2782264

Détail du produit anti-HNF4A anticorps

Antigène: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Mouton, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF4A est non-conjugé

Application: Western Blotting (WB)

Séquence: LPFQELQIDD NEYAYLKAII FFDPDAKGLS DPGKIKRLRS QVQVSLEDYI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HNF4A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HNF4A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 442 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HNF4A

Antigène: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Autre désignation: HNF4A (HNF4A Produits)

Synonymes: anticorps HNF4A, anticorps HNF4alpha, anticorps CG9310, anticorps DmHNF4, anticorps Dmel\\CG9310, anticorps HNF-4, anticorps HNF-4(D), anticorps HNF4, anticorps Hnf-4, anticorps Hnf-4h, anticorps NR2A4, anticorps dHNF-4, anticorps dHNF4, anticorps Hnf4, anticorps Hnf4alpha, anticorps MODY1, anticorps Nr2a1, anticorps Tcf14, anticorps HNF4a7, anticorps HNF4a8, anticorps HNF4a9, anticorps MODY, anticorps NR2A1, anticorps NR2A21, anticorps TCF, anticorps TCF14, anticorps HNF-4alpha, anticorps fb58h09, anticorps id:ibd1279, anticorps wu:fb58h09, anticorps hnf4, anticorps nr2a1, anticorps hepatocyte nuclear factor 4 alpha, anticorps Hepatocyte nuclear factor 4, anticorps hepatic nuclear factor 4, alpha, anticorps hepatocyte nuclear factor 4, alpha, anticorps hepatocyte nuclear factor 4 alpha S homeolog, anticorps HNF4A, anticorps hnf4a, anticorps Hnf4, anticorps Hnf4a, anticorps hnf4a.S

Sujet: The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: FLJ39654, HNF4, HNF4a7, HNF4a8, HNF4a9, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14, HNF4alpha
Protein Interaction Partner: PIAS4, SUMO1, SUMO2, RNF4, SUB1, CREBBP, TBP, TAF9, TAF6, TADA2A, GTF2H1, GTF2B, ANP32B, MDM2, GPS2, PPARGC1A, HNF4A, NCOA6, SMAD4, SMAD3, PNRC2, COPS5, PNRC1, NR0B2, NRIP1, UBE2I, PROX1, NPPA, SREBF2, VDR, MAPK3, MAPK1, SIRT1, SREBF1, XPO1, SP1, HDAC3, T
Protein Size: 442

Poids moléculaire: 49 kDa

ID gène: 3172

NCBI Accession: NM_001030003, NP_001025174

UniProt: P41235

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process