IGFBP4 anticorps (Middle Region)

N° du produit ABIN2782316

Cet anticorps Lapin Polyclonal détecte spécifiquement IGFBP4 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chévre, Chien, Cheval, Lapin, Mouton et Cobaye et a été mentionné dans 1 publication.

Aperçu rapide pour IGFBP4 anticorps (Middle Region) (ABIN2782316)

Antigène: IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Chien, Cheval, Lapin, Mouton, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGFBP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-IGFBP4 anticorps

Épitope: Middle Region

Séquence: RALERLAASQ SRTHEDLYII PIPNCDRNGN FHPKQCHPAL DGQRGKCWCV

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against IGFBP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human IGFBP4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 258 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-IGFBP4 (ABIN2782316)

Shi, Chiang, Mistretta, Major, Mori-Akiyama: "SOX9 directly regulates IGFBP-4 in the intestinal epithelium." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 305, Issue 1, pp. G74-83, (2013) (PubMed).

Détails sur IGFBP4

Antigène: IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))

Autre désignation: IGFBP4

Sujet: IGFBP4 is a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 is a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BP-4, HT29-IGFBP, IBP4, IGFBP-4
Protein Interaction Partner: KDM1A, SUV39H1, Hk3, Hk2, TF, PAPPA, IGF2, IGF1, CTSD,
Protein Size: 258

Poids moléculaire: 28 kDa

ID gène: 3487

NCBI Accession: NM_001552, NP_001543

UniProt: P22692

Pathways: Signalisation WNT, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process