SIK1 anticorps (Middle Region)

N° du produit ABIN2782412

Cet anticorps Lapin Polyclonal détecte spécifiquement SIK1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cheval, Chien, Cobaye et Poisson zèbre (Danio rerio) et a été mentionné dans 1 publication.

Aperçu rapide pour SIK1 anticorps (Middle Region) (ABIN2782412)

Antigène: SIK1 (Salt-Inducible Kinase 1 (SIK1))

Reactivité: Humain, Souris, Rat, Cheval, Chien, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SIK1 anticorps

Épitope: Middle Region

Séquence: TPVLQSQAGL GATVLPPVSF QEGRRASDTS LTQGLKAFRQ QLRKNARTKG

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Sik1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 776 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SIK1 (ABIN2782412)

McTague, Ferguson, Chik, Ho: "The adrenergic-regulated CRTC1 and CRTC2 phosphorylation and cellular distribution is independent of endogenous SIK1 in the male rat pinealocyte." dans: Molecular and cellular endocrinology, Vol. 414, pp. 156-67, (2015) (PubMed).

Détails sur SIK1

Antigène: SIK1 (Salt-Inducible Kinase 1 (SIK1))

Autre désignation: Sik1

Sujet: Sik1 inhibits CREB binding and transcription of cAMP-responsive element (CRE)-dependent genes Cyp11A and Star.
Alias Symbols: Sik, Snf1lk
Protein Size: 776

Poids moléculaire: 85 kDa

ID gène: 59329

NCBI Accession: NM_021693, NP_067725

UniProt: Q9R1U5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process