RRM2B anticorps (Middle Region)

N° du produit ABIN2782441

Détail du produit anti-RRM2B anticorps

Antigène: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Cheval, Porc, Chien, Cobaye, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRM2B est non-conjugé

Application: Western Blotting (WB)

Séquence: VHSEMYSLLI DTYIRDPKKR EFLFNAIETM PYVKKKADWA LRWIADRKST

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Yeast: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against RRM2B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human RRM2B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RRM2B

Antigène: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Autre désignation: RRM2B (RRM2B Produits)

Synonymes: anticorps p53r2, anticorps RRM2B, anticorps MTDPS8A, anticorps MTDPS8B, anticorps P53R2, anticorps p53R2, anticorps ribonucleotide reductase M2 B (TP53 inducible) S homeolog, anticorps ribonucleotide reductase regulatory TP53 inducible subunit M2B, anticorps ribonucleotide reductase M2 B (TP53 inducible), anticorps rrm2b.S, anticorps RRM2B, anticorps rrm2b, anticorps Rrm2b

Sujet: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Protein Interaction Partner: RRM2B, ORC4, UBC, AICDA, RRM1, TP53, RRM2, MDM2, ATM, ZBTB17, MYC,
Protein Size: 299

Poids moléculaire: 32 kDa

ID gène: 50484

Pathways: Signalisation p53, Negative Regulation of intrinsic apoptotic Signaling