CENPA anticorps (N-Term)

N° du produit ABIN2782448

L’anticorps anti-CENPA Polyclonal Lapin est utilisé pour la détection de CENPA dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et IHC.

Aperçu rapide pour CENPA anticorps (N-Term) (ABIN2782448)

Antigène: CENPA (Centromere Protein A (CENPA))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CENPA anticorps

Épitope: N-Term

Fonction: CENPA Antibody - N-terminal region

Séquence: MGPRRRSRKP EAPRRRSPSP TPTPGPSRRG PSLGASSHQH SRRRQGWLKE

Homologie: Human: 100%, Mouse: 90%, Rat: 90%

Attributs du produit: This is a rabbit polyclonal antibody against CENPA. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CENPA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096714

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CENPA

Antigène: CENPA (Centromere Protein A (CENPA))

Autre désignation: CENPA

Sujet:

Background Information: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.

Gene Name: Centromere protein A

Alternative Symbols: CenH3, CENP-A

Protein Name: Histone H3-like centromeric protein A

Poids moléculaire: 16kDa

ID gène: 1058

NCBI Accession: NP_001800

UniProt: P49450

Pathways: Chromatin Binding, Maintenance of Protein Location